Application of the MBS

Use Cases

Diagnosis

USE CASE

Determining the cause of acute lower respiratory diseases, such as community acquired pneumonia and exacerbations in chronic respiratory patients.

ADVANTAGES

Providing a sample from the site of infection, allowing for unambiguous diagnostic results within the "golden" hour, enabling directed therapy in a timely fashion.

VALIDATION

Assessment of COPD patients admitted with an exacerbation (unpublished).

The Clinical Sample of Choice for Diagnosing Lung Infections

Better sample, Better treatment!​

USE CASE

Early detection of respiratory pathogens in patients with Chronic Respiratory Disease, e.g. CF and COPD.

ADVANTAGES

Easy-of-use and low sampling burden allow for daily or even hourly sampling, enabling health monitoring of the lower respiratory tract and early treatment, avoiding under- or over-treatment and herewith exacerbations.

VALIDATION

Non-invasive diagnostics of pathogenic bacteria using a breath sampler in children with cystic fibrosis’, K. J. van Aerde, et al., Journal of Breath Research, 2022.

Monitoring

Unambiguous Diagnosis is Hampered by Conventional Sampling Methods

Better sample, Better treatment!​

Contagiousness

USE CASE

More relevant than ever, safeguarding medical personnel and determining if a patient should be isolated or can go home to recover.

ADVANTAGES

The mere presence of pathogens in conventional samples does not determine contagiousness, however, the presence in aerosols does.

VALIDATION

‘SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients’, L. Kurver, et al., Scientific Reports, 2022.

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About

Xheal Diagnostics B.V. is a start-up company and spin-off of the Radboudumc focussed sampling innovations for the lower respiratory tract. Our proprietary exhaled breath sampling technology enables a timely and better diagnosis of lung infections and hence improves patient care.

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